We all know that our immune antibody responses are specific to the particular antigen invading our body. However, our immune response is also geared for non-specific protection. For example, activated macrophages induced by salmonella can also attack other intracellular pathogens such as listeria.
A recent study in mice showed that even latent infection by herpes induces a prolonged stage of macrophage activation that gives protection from other infections. Keeping the immune system alert like this may therefore confer benefits.
Does a higher antigenic load lead to a better and more mature immune system?
Emil R. Unanue. NEJM 2007; 357: 1345
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment